"I was surprised that heart disease was the number one killer" of women, Bush says. "I just didn't know. I assumed cancer was. And I knew if I didn't know, most women probably didn't know either."

The first lady has spent five years delivering the campaign's message that heart disease affects women as much as men, that a woman's heart attack symptoms can be very different from a man's and that women need to know if their family history or their lifestyle puts them at risk for heart disease.